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Publication : Testosterone and the sex difference in blood pressure in mice.

First Author  Schmalbach NL Year  1976
Journal  Pharmacol Biochem Behav Volume  4
Issue  3 Pages  339-41
PubMed ID  935204 Mgi Jnum  J:36393
Mgi Id  MGI:83826 Doi  10.1016/0091-3057(76)90252-5
Citation  Schmalbach NL, et al. (1976) Testosterone and the sex difference in blood pressure in mice. Pharmacol Biochem Behav 4(3):339-41
abstractText  Blood pressure of adult male SWR/J mice is approximately 20 mm Hg higher than that of females. Castrating males at weaning eliminated this sex difference. Testosterone restored blood pressure of castrated mice to the level of the intact males within 10 days indicating a pressor effect of testosterone. Ovariectomy had no effect on blood pressure.
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