| Primary Identifier | MGI:1923159 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 75909 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable phospholipid scramblase activity. Involved in autophagy and lipoprotein transport. Acts upstream of or within embryo implantation. Located in phagophore assembly site. Orthologous to human VMP1 (vacuole membrane protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality between E7.5 and E9.5 with reduced size at E7.5 and neutral lipid accumulation in visceral endoderm cells. Mice homozygous for a conditional allele activated in intestinal epithelia exhibit reduced body weight and neutral lipid accumulation in intestinal epithelia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
