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Protein Coding Gene : Kcnmb1 potassium large conductance calcium-activated channel, subfamily M, beta member 1

Primary Identifier  MGI:1334203 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  16533
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables calcium-activated potassium channel activity. Acts upstream of or within potassium ion transmembrane transport. Located in membrane. Part of voltage-gated potassium channel complex. Is expressed in arterial system; sensory organ; skeleton; and tarsus. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human KCNMB1 (potassium calcium-activated channel subfamily M regulatory beta subunit 1).
PHENOTYPE: Homozygous mutation of this gene results in increased blood pressure, and impaired motor coordination and cerebellar function. [provided by MGI curators]
  • synonyms:
  • BK channel beta subunit,
  • potassium large conductance calcium-activated channel, subfamily M, beta member 1,
  • BKbeta1,
  • Kcnmb1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For