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Allele : Tg(tetO/CMV-CFTR)TC35Clh transgene insertion TC35, Clare Huxley
Primary Identifier  MGI:5318248 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence Gene  Tg(tetO/CMV-CFTR)TC35Clh
Strain of Origin  C57BL/6J x CBA/Ca Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  This transgene contains a cDNA encoding the human cystic fibrosis transmembrane conductance regulator (CFTR) cloned into plasmid pUHD.10-3 between the PhCMV*-1 tetracycline-inducible promoter -- which is composed of a heptamer of the 19-base pair direct repeat tetracycline operator (tetO) followed by the human cytomegalovirus (CMV) immediate early (IE) minimal promoter, extending from nucleotide (nt) -53 to nt +75 -- and the SV40 polyadenylation signal.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(CMV-tetO-CFTR)TC35CH,
  • Tg(CMV-tetO-CFTR)TC35CH
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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