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Allele : Mia3<tm1Lex> MIA SH3 domain ER export factor 3; targeted mutation 1, Lexicon Pharmaceuticals

Primary Identifier  MGI:5007248 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Mia3
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
Project Collection  Lexicon
description  See also, data as provided by Lexicon Genetics, Inc.
molecularNote  A lacZ/neo fusion cassette was inserted in frame 11 bases into the beginning of the second exon, replacing this exon and all of exon3. Western blot analysis confirmed the absence of the large SH3 domain containing isoform and the presence of an about 80-90 kD isoform lacking the SH3 domain in homozygous embryos.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele