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Allele : Mecp2<tm2.1Meg> methyl CpG binding protein 2; targeted mutation 2.1, Michael E Greenberg
Primary Identifier  MGI:5529372 Allele Type  Targeted
Gene  Mecp2 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  Nucleotide substitution(s) in exon 4 resulted in the amino acid substitution of cysteine for arginine at position 306 (R306C). This mutation abolishes the interaction with NCoR/SMRT components. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of exon 4.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Mecp2<R306C>,
  • Mecp2<R306C>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele




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