Primary Identifier | MGI:1914848 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 56207 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable cysteine-type deubiquitinase activity; endopeptidase inhibitor activity; and proteasome binding activity. Involved in several processes, including brain development; positive regulation of DNA metabolic process; and telomere maintenance. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of Ino80 complex and cytosolic proteasome complex. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain ventricular layer; genitourinary system; nose; and salivary gland primordium. Orthologous to human UCHL5 (ubiquitin C-terminal hydrolase L5). PHENOTYPE: Mice homozygous for a gene trap allele exhibit embryonic lethality associated with abnormal brain development. [provided by MGI curators] |