| First Author | Jongstra J | Year | 1981 |
| Journal | J Virol | Volume | 37 |
| Issue | 3 | Pages | 1044-50 |
| PubMed ID | 6164797 | Mgi Jnum | J:33305 |
| Mgi Id | MGI:80785 | Doi | 10.1128/jvi.37.3.1044-1050.1981 |
| Citation | Jongstra J, et al. (1981) Lipopolysaccharide induces retroviral antigen expression in 129/J mouse lymphocytes: evidence for assembly of a defective viral particle. J Virol 37(3):1044-50 |
| abstractText | In contrast to those of many other mouse strains, spleen cell cultures of 129/J mice do not release reverse transcriptase activity into the supernatant upon stimulation with bacterial lipopolysaccharide. We report here that lipopolysaccharide induced the expression of intracellular viral proteins in 129/J spleen cells. Furthermore, we found that stimulated spleen cells released retroviral particles. We conclude that 129/J mice are inducible with lipopolysaccharide but that the virus produced is a defective particle deficient in reverse transcriptase activity. |
