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Allele : Nkx2-5<tm1.1(cre/ERT2)Rard> NK2 homeobox 5; targeted mutation 1.1, Reza Ardehali

Primary Identifier  MGI:6791388 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Nkx2-5
Transmission  Germline Strain of Origin  Not Specified
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  Using homologous recombination in ES cells an internal ribosome entry site (IRES) linked to the gene encoding a nuclear-localizing recombinase cre fused to ERT2 and a hygromycin resistance gene cassette (pgk-HYGROpA) flanked by yeast flp recombinase target (frt) sites was inserted into the 3' UTR of the endogenous locus. pgk-HYGRO-pA cassette was removed by crossing to Flp recombinase gene expressing mice.
  • mutations:
  • Insertion
  • synonyms:
  • Nkx2-5/CreER,
  • Nkx2-5/CreER
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

4 Publication categories

Trail: Allele