Primary Identifier | MGI:6286293 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Cd79b |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4029 |
molecularNote | ENU-induced G to A transition at base pair 106,312,713 (v38) on chromosome 11, or base pair 1,850 in the GenBank genomic region NC_000077. The mutation corresponds to residue 425 in the mRNA sequence NM_008339 within exon 3 of 6 total exons. The mutation results in a glycine to aspartic acid substitution at position 116 (G116D) in the CD79B protein. |