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Protein Domain : C-C motif chemokine 22

Primary Identifier  IPR030598 Type  Family
Short Name  CCL22
description  Macrophage-derived chemokine or CC chemokine 22 (MDC/CCL22) is a chemokine produced by macrophages and dendritic cells []. It is a chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells []. It binds to receptor CCR4 [, ]. MDC/CCL2 may play an important role in the recruitment of TH2 cells into the inflammatory sites and the regulation of T helper type 2 (TH2)-related immune responses [, ].

0 Child Features

1 Parent Features

3 Protein Domain Regions