Primary Identifier | MGI:1920713 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 73463 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in flagellated sperm motility; sperm capacitation; and vesicle-mediated transport to the plasma membrane. Located in sperm principal piece. Part of CatSper complex. Human ortholog(s) of this gene implicated in spermatogenic failure. Orthologous to human C2CD6 (C2 calcium dependent domain containing 6). PHENOTYPE: Mice homozygous for a null allele exhibit male infertility associated with decreased hyperactivate sperm motility and reduced Cat Sper calcium channel capacity. [provided by MGI curators] |