| Primary Identifier | MGI:1914596 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 208846 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable identical protein binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to act upstream of or within Wnt signaling pathway. Located in perinuclear region of cytoplasm and stress fiber. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; genitourinary system; and gut. Used to study intrinsic cardiomyopathy. Orthologous to human DAAM1 (dishevelled associated activator of morphogenesis 1). PHENOTYPE: Homozygotes for a gene trap allele show reduced fetal size, partial embryonic and neonatal lethality, altered cytoskeletal structure, cardiac defects including ventricular noncompaction, double outlet right ventricles and ventricular septal defects, and impaired cell adhesion and wound healing. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
