| Primary Identifier | MGI:3765940 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Stx1b |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A vector was designed to introduce two modified copies of exon 7 to the targeted gene. The first modified exon 7 carries a partial cDNA fragment of syntaxin with a C-terminal GFP and a stop codon. This mutation is followed by neomycin resistance cassette placed in intron 7 and flanked by flp sites. The first exon 7 insertion and the neomycin cassette are flanked by a pair of loxP sites. A second modified exon 7 bearing L165A and E166A mutations follows the neomycin insertion. |
