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Allele : Igs2<em62(tetO-APOBEC1*/cas9*,CAG-rtTA)Gpt> intergenic site 2; endonuclease-mediated mutation 62, GemPharmatech Co., Ltd
Primary Identifier  MGI:7300675 Allele Type  Endonuclease-mediated
Attribute String  Endonuclease, Inducible, Inserted expressed sequence Gene  Igs2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6JGpt
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting inserted a tetracycline response element driving inducible expression of a recombinant APOBEC1 (W90Y, R126E) fused with a cas( containing the amino acid substitution of aspartic acid with alanine at position 10 (D10A). The insertion also contains a CAG promoter dirving ubiquitous expression of a reverse tetracycline transactivator.
  • mutations:
  • Insertion
  • synonyms:
  • Igs2<em1Cin(pTRE3G-YE1-BE4max-rTTA-CAG)>,
  • Igs2<em1Cin(pTRE3G-YE1-BE4max-rTTA-CAG)>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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