| Primary Identifier | MGI:7300676 | Allele Type | Endonuclease-mediated |
| Attribute String | Endonuclease, Inducible, Inserted expressed sequence | Gene | Igs2 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6JGpt |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | CRISPR-targeting inserted the tetracycline response element driving inducible expression of the E. coli tRNA adenosine deaminase with the mutation encoding the amino acid substitution of valine with tryptophan at position 106 (V106W) fused with cas9 endonuclease. The insertion also carries a cassette composed of a CAG promoter and reverse tetracycline transactivator. |
