| Primary Identifier | IPR037982 | Type | Domain |
| Short Name | TDRD5_LOTUS_2 |
| description | TDRD5 belongs to the evolutionary conserved Tudor domain-containing protein (TDRD) family involved in germ cell development. In mice, TDRD5 is a component of the intermitochondrial cements (IMCs) and the chromatoid bodies (CBs), which are cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis [].TDRD5 contains three N-terminal LOTUS domains and a C-terminal Tudor domain. This entry represents the second LOTUS domain of TDRD5. The LOTUS domain adopts the winged helix-turn-helix fold and may bind RNA [, ]. |
