| Primary Identifier | MGI:2447992 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 433766 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables ubiquitin protein ligase activity. Involved in protein monoubiquitination and response to denervation involved in regulation of muscle adaptation. Acts upstream of or within cellular response to dexamethasone stimulus; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of gene expression. Predicted to be located in contractile fiber. Predicted to be active in cytoplasm. Is expressed in embryo and heart. Orthologous to human TRIM63 (tripartite motif containing 63). PHENOTYPE: A targeted homozygous mutation in this gene results in resistance to skeletal muscle atrophy in response to nerve injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
