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Publication : Rapid localization of membrane skeletal protein 4.1 (EL1) to human chromosome 1p33----p34.2 by nonradioactive in situ hybridization.

First Author  Tang CJ Year  1991
Journal  Cytogenet Cell Genet Volume  57
Issue  2-3 Pages  119
PubMed ID  1914519 Mgi Jnum  J:11455
Mgi Id  MGI:59889 Doi  10.1159/000133128
Citation  Tang CJ, et al. (1991) Rapid localization of membrane skeletal protein 4.1 (EL1) to human chromosome 1p33----p34.2 by nonradioactive in situ hybridization. Cytogenet Cell Genet 57(2-3):119
abstractText  Hereditary elliptocytosis (HE) is a heterogeneous group of red-cell disorders. One class of HE patients was shown to have a mutated erythrocyte membrane skeletal protein 4.1 gene. We have recently shown that human protein 4.1 contains multiple isoforms with novel sizes, functions, and tissue-specific expression. Here, we report the subregional localization of this gene to human chromosome 1p33----p34.2, based on the fractional length, by nonradioactive in situ hybridization.
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