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Protein Coding Gene : Tac2 tachykinin 2

Primary Identifier  MGI:98476 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  21334
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable neuromedin K receptor binding activity and substance K receptor binding activity. Predicted to be involved in positive regulation of blood pressure and positive regulation of flagellated sperm motility. Predicted to act upstream of or within neuropeptide signaling pathway. Predicted to be located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 10 with or without anosmia. Orthologous to human TAC3 (tachykinin precursor 3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit delayed female sexual maturation and fertility. [provided by MGI curators]
  • synonyms:
  • neurokinin alpha,
  • neuropeptide K,
  • MGD-MRK-14703,
  • neurokinin 2,
  • Tac2,
  • neurokinin A,
  • neuromedin L,
  • tachykinin 2,
  • substance K

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

3 Driver For