First Author | Seharaseyon J | Year | 1990 |
Journal | Genomics | Volume | 7 |
Issue | 2 | Pages | 289-93 |
PubMed ID | 2129532 | Mgi Jnum | J:10539 |
Mgi Id | MGI:58989 | Doi | 10.1016/0888-7543(90)90554-8 |
Citation | Seharaseyon J, et al. (1990) Human embryonic/atrial myosin alkali light chain gene: characterization, sequence, and chromosomal location. Genomics 7(2):289-93 |
abstractText | We have isolated and sequenced the gene encoding the human embryonic/atrial myosin alkali light chain isoform (MLC-1emb/A). The gene is split into seven exons by six introns; the last exon, as in all MLC isoform genes sequenced to date, is completely 3' untranslated sequence. Comparison of the MLC-1emb/A isoform gene with the other MLC-1 genes showed that the exon-intron arrangement of the human MLC-1emb/A isoform gene is analogous to that of the other MLC-1 type isoform genes. We have also mapped the human MLC-1emb/A isoform gene to the long arm of chromosome 17; the corresponding mouse gene has been mapped to chromosome 11. This gene, together with a number of others such as the collagen(I) alpha 1, galactokinase, and thymidine kinase genes, is part of the largest syntenic group between mouse and man. |