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Protein Coding Gene : Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

Primary Identifier  MGI:95653 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  14447
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in flagellated sperm motility. Acts upstream of or within glycolytic process. Located in sperm fibrous sheath and sperm principal piece. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic).
PHENOTYPE: Homozygous null mice display male infertility and asthenozoospermia. [provided by MGI curators]
  • synonyms:
  • glyceraldehyde-3-phosphate dehydrogenase, spermatogenic,
  • MGD-MRK-9980,
  • MGD-MRK-9981,
  • Gapdhs,
  • Gapd-s,
  • Gapds

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For