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Protein Coding Gene : Ric8a RIC8 guanine nucleotide exchange factor A

Primary Identifier  MGI:2141866 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  101489
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G-protein alpha-subunit binding activity; GTPase activator activity; and guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including basement membrane organization; gastrulation; and visual learning. Located in membrane. Is expressed in several structures, including alimentary system; extraembryonic component; female reproductive system; nervous system; and sensory organ. Orthologous to human RIC8A (RIC8 guanine nucleotide exchange factor A).
PHENOTYPE: Homozygous mutation of this gene results in lethality during gastrulation. Heterozygotes exhibit impaired spatial learning and increased anxiety. [provided by MGI curators]
  • synonyms:
  • resistance to inhibitors of cholinesterase 8 homolog (C. elegans),
  • Ric8a,
  • synembryn,
  • AI114950,
  • expressed sequence AI114950,
  • RIC8 guanine nucleotide exchange factor A,
  • RIC-8,
  • Ric8

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For