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Protein Coding Gene : Pex5l peroxisomal biogenesis factor 5-like

Primary Identifier  MGI:1916672 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  58869
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable intracellularly cyclic nucleotide-activated monoatomic cation channel activity; peroxisome matrix targeting signal-1 binding activity; and small GTPase binding activity. Acts upstream of or within maintenance of protein location and regulation of membrane potential. Located in cytoplasm and dendrite. Is expressed in brain; cerebral cortex; and retina outer nuclear layer. Orthologous to human PEX5L (peroxisomal biogenesis factor 5 like).
PHENOTYPE: Mice homozygous for a targeted mutation lacking isoform b exhibit reduced hyperpolarization-activated current in CA1 pyramidal neuron, impaired motor learning, impaired nest-building, decreased startle reflex, and decreased depression-related behaviors. [provided by MGI curators]
  • synonyms:
  • peroxin 2,
  • TRIP8b,
  • RIKEN cDNA 1700016J08 gene,
  • Pex2,
  • Pex5l,
  • peroxisomal biogenesis factor 5-like,
  • 1700016J08Rik,
  • PXR2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For