Primary Identifier | MGI:2384631 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Cd79a |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2 through 5 were replaced by a fragment flanked by inverted loxP sites and containing sequence encoding a membrane-associated enhanced green fluorescent protein (GFP) followed downstream by a polyA signal and, in opposite orientation, the coding regions of exons 2 through 5. The absence of endogenous protein and the expression of GFP was confirmed by flow cytometric analysis of bone marrow, spleen, and lymph node cells. |