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Protein Coding Gene : Pkm pyruvate kinase, muscle
Primary Identifier  MGI:97591 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  18746
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables mRNA binding activity and pyruvate kinase activity. Involved in canonical glycolysis and positive regulation of cytoplasmic translation. Located in cilium and rough endoplasmic reticulum. Is active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PKM (pyruvate kinase M1/2).
PHENOTYPE: Mice homozygous for a spontaneous allele exhibit prenatal lethality around the time of implanatation. [provided by MGI curators]
  • synonyms:
  • AA414905,
  • AL024424,
  • Pk-2,
  • MGI:2143184,
  • Pk3,
  • MGI:2143183,
  • pyruvate kinase, muscle,
  • pyruvate kinase,
  • AL024370,
  • expressed sequence AA414905,
  • MGD-MRK-13319,
  • Pk-3,
  • Pkm2,
  • pyruvate kinase 3,
  • expressed sequence AL024370,
  • MGD-MRK-13320,
  • expressed sequence AL024424,
  • MGI:2144733,
  • MGD-MRK-13322,
  • Pkm
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Canonical gene --> Transcripts in specific strains.

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Trail: ProteinCodingGene

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Genes/Features --> Phenotypes (MP terms)

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