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Publication : Characterization of Opr deficiency in mouse brain: subtle defects in dorsomedial telencephalon and medioventral forebrain.

First Author  Furushima K Year  2005
Journal  Dev Dyn Volume  232
Issue  4 Pages  1056-61
PubMed ID  15736266 Mgi Jnum  J:97076
Mgi Id  MGI:3574232 Doi  10.1002/dvdy.20253
Citation  Furushima K, et al. (2005) Characterization of Opr deficiency in mouse brain: Subtle defects in dorsomedial telencephalon and medioventral forebrain. Dev Dyn 232(4):1056-61
abstractText  Opr/Zic5 is a zinc-finger gene belonging to, and unique in, the opa/Zic family. Its expression is found in the anterior epiblast and anterior neuroectoderm during gastrulation and early neurulation. Later, we found the expression characteristic in the dorsomedial parts of forebrain and midbrain. However, no defects were apparent in embryonic day 10.5 Opr null mutants, and subtle defects were later found in medial pallium and ventral structures of forebrain, suggesting the compensation of Opr deficiency by its cognate(s). Developmental Dynamics 232:1056-1061, 2005. (c) 2005 Wiley-Liss, Inc.
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