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Protein Coding Gene : Izumo1 izumo sperm-egg fusion 1

Primary Identifier  MGI:1920706 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  73456
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables protein binding activity involved in heterotypic cell-cell adhesion; protein homodimerization activity; and signaling receptor binding activity. Involved in fusion of sperm to egg plasma membrane involved in single fertilization; heterotypic cell-cell adhesion; and sperm-egg recognition. Located in acrosomal membrane; endoplasmic reticulum membrane; and plasma membrane. Part of protein complex involved in cell-cell adhesion. Orthologous to human IZUMO1 (izumo sperm-oocyte fusion 1).
PHENOTYPE: Homozygous null male mice are infertile due to inability of sperm to fuse with the egg. [provided by MGI curators]
  • synonyms:
  • 1700058F15Rik,
  • Izumo1,
  • RIKEN cDNA 1700058F15 gene,
  • izumo sperm-egg fusion 1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For