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Publication : Smoothing out drug resistance.

First Author  Kasper M Year  2013
Journal  Cancer Cell Volume  23
Issue  1 Pages  3-5
PubMed ID  23328478 Mgi Jnum  J:194345
Mgi Id  MGI:5473461 Doi  10.1016/j.ccr.2012.12.011
Citation  Kasper M, et al. (2013) Smoothing out drug resistance. Cancer Cell 23(1):3-5
abstractText  Smoothened inhibitors have emerged as successful treatment alternatives for Hedgehog pathway-dependent tumors, but they are linked with the appearance of drug resistance. In this issue of Cancer Cell, Kim and colleagues overcome such resistance by combining approved drugs itraconazole and arsenic trioxide, thus opening a path toward new treatment options.
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