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Allele : Casp1<tm1Flv> caspase 1; targeted mutation 1, Richard Flavell

Primary Identifier  MGI:2158744 Allele Type  Targeted
Attribute String  Null/knockout Gene  Casp1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
description  The ES cells used to generate this allele contain the linked Casp4del truncated allele that fails to produce a functional Casp4. Phenotypes associated with this allele may be affected by the presence of the Caspdel allele. J:193522
molecularNote  A genomic fragment containing part of exon 6 and exon 7 was replaced with a neomycin selection cassette. RT-PCR analysis on samples derived from homozygous mice demonstrated that no detectable transcript was produced from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • ICE-,
  • Casp1<->,
  • ICE-,
  • caspase-1-,
  • caspase-1-,
  • Casp1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

451 Publication categories

Trail: Allele