| First Author | Thurston MN | Year | 1985 |
| Journal | J Anat | Volume | 140 ( Pt 3) |
| Pages | 425-34 | PubMed ID | 3840788 |
| Mgi Jnum | J:8099 | Mgi Id | MGI:56568 |
| Citation | Thurston MN, et al. (1985) Cell kinetics of growth cartilage of achondroplastic (cn) mice. J Anat 140(Pt 3):425-34 |
| abstractText | Mice homozygous for the recessive gene achondroplasia (cn) aged 16 and 17 days and some homozygotes aged 22-34 days have disruptions in the growth of the proximal tibial growth plate which are due solely to reduced hypertrophic cell height. A second class of homozygote, distinguishable at 22 days, has a greater disruption due to much reduced hypertrophic cell height, reduced labelling index and reduction of the number of cells in the effective proliferative zone. |
