| Primary Identifier | MGI:88578 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 13063 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables heme binding activity. Acts upstream of or within apoptotic process and hydrogen peroxide metabolic process. Located in cytosol and mitochondrion. Is expressed in several structures, including central nervous system; jaw; limb; metanephros; and spiral ligament. Human ortholog(s) of this gene implicated in cholangiocarcinoma; lung non-small cell carcinoma; pancreatic cancer; and thrombocytopenia. Orthologous to human CYCS (cytochrome c, somatic). PHENOTYPE: Mice homozygous for a targeted mutation die at midgestation. By E8.5, homozygous null embryos exhibit a strikingly reduced size and are developmentally retarded. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
