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Protein Coding Gene : Arhgap26 Rho GTPase activating protein 26
Primary Identifier  MGI:1918552 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  71302
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GTPase activator activity and phospholipid binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytosol and endosome membrane. Is expressed in amygdala; diencephalon lateral wall mantle layer; hypothalamus mantle layer; olfactory epithelium; and telencephalon mantle layer. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia and juvenile myelomonocytic leukemia. Orthologous to human ARHGAP26 (Rho GTPase activating protein 26).
PHENOTYPE: Mice homozygous for a hypomorphic allele display reduced myofiber size, impaired myoblast fusion and abnormal muscle regeneration. [provided by MGI curators]
  • synonyms:
  • Arhgap26,
  • MGI:2147280,
  • Rho GTPase activating protein 26,
  • MGI:1917571,
  • RIKEN cDNA 2610010G17 gene,
  • mKIAA0621,
  • RIKEN cDNA 1810044B20 gene,
  • RIKEN cDNA 4933432P15 gene,
  • 1810044B20Rik,
  • AI853435,
  • 2610010G17Rik,
  • expressed sequence AI853435,
  • 4933432P15Rik,
  • MGI:1917050
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