| Primary Identifier | MGI:2140726 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231279 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable mitochondrial ribosome binding activity. Predicted to be involved in positive regulation of translation. Predicted to act upstream of or within translation. Located in mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 40. Orthologous to human GUF1 (GTP binding elongation factor GUF1). PHENOTYPE: Mice homozygous for a null allele exhibit male infertility, decreased testis weight, oligozoospermia, asthenozoospermia, increased male germ cell apoptosis, and fractured or torn away sperm mitochondrial sheath with aberrant mitochondria that lack the inner-membrane system. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
