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Allele : Dct<em2Jkn> dopachrome tautomerase; endonuclease-mediated mutation 2, Ian J Jackson

Primary Identifier  MGI:6831165 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Dct
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a C to G change at position 183 (c.183C>G) resulting in a cysteine to tryptophan substitution at residue 61 (p.Cys61Trp). This is a variant identified in a patient with oculocutanous albinism.
  • mutations:
  • Single point mutation
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele