| Primary Identifier | IPR036042 | Type | Domain |
| Short Name | MYSc_Myo16 |
| description | Type XVI myosin (Myo16) is also known as neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3/NYAP3. Myo16 is thought to play a regulatory role in cell cycle progression and has been implicated in schizophrenia [, ]. Class XVI myosins are characterized by an N-terminal ankyrin repeat domain thought to bind protein phosphatase 1 catalytic subunits 1alpha/PPP1CA and 1gamma/PPP1CC []. Myo16 interacts with phosphoinositide 3-kinase and the components of the WAVE1 complex []. The catalytic (head) domain may not act as a molecular motor as sequence analysis of the ATP-binding site predicted reduced ATPase activity []. |
