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Allele : Runx1<tm1.1(RUNX1*)Homy> runt related transcription factor 1; targeted mutation 1.1, Hiroaki Honda
Primary Identifier  MGI:4835663 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph, Inserted expressed sequence Gene  Runx1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A cellular IRES in the 5' UTR of exon 3, the coding region of exon 3 and part of intron 3 were replaced with a floxed complete human RUNX1 splice variant B cDNA and an FRT flanked neo cassette via homologous recombination. The neo cassette was removed by flp mediated recombination. Blotting analysis indicated protein expression in whole homozygous embryos at E13.5 is similar to wild-type controls.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Runx1<deltaIRES>,
  • Runx1<deltaIRES>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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