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Protein Coding Gene : Cdk11b cyclin dependent kinase 11B
Primary Identifier  MGI:88353 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  12537
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Acts upstream of or within blastocyst development; negative regulation of apoptotic signaling pathway; and regulation of mitotic nuclear division. Located in nucleus. Is expressed in several structures, including alimentary system; brain; early embryo; integumental system; and submandibular gland primordium. Orthologous to several human genes including CDK11B (cyclin dependent kinase 11B).
PHENOTYPE: Homozygous null embryos display embryonic lethality from cell cycle arrest. [provided by MGI curators]
  • synonyms:
  • Cdc2l1,
  • PITSLRE proteins,
  • cyclin dependent kinase 11B,
  • CDK11-p58,
  • MGI:2140185,
  • Cdc2l2,
  • MGI:1098660,
  • AA989746,
  • CDK11-p46,
  • MGD-MRK-1880,
  • expressed sequence AA989746,
  • CDK11-p110,
  • cell division cycle 2-like 1,
  • cell division cycle 2 homolog (S. pombe)-like 2,
  • Cdk11b
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Homology

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Interactions

6 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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