Primary Identifier | MGI:1915831 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 68581 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cargo receptor activity; protein transmembrane transporter activity; and syntaxin binding activity. Involved in several processes, including positive regulation of interleukin-1 production; positive regulation of protein secretion; and vesicle targeting, to, from or within Golgi. Located in zymogen granule membrane. Part of gamma-secretase complex. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human TMED10 (transmembrane p24 trafficking protein 10). PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality before implantation. Heterozygous mice display abnormalities of the Golgi apparatus. [provided by MGI curators] |