Primary Identifier | MGI:2138614 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 227210 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity. Involved in neurogenesis and regulation of canonical Wnt signaling pathway. Acts upstream of or within flagellated sperm motility; regulation of protein phosphorylation; and spermatogenesis. Located in plasma membrane. Is expressed in several structures, including genitourinary system; gut; liver; mammary gland; and spleen. Orthologous to human CCNYL1 (cyclin Y like 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with asthenozoospermia and teratozoospermia. [provided by MGI curators] |