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Protein Coding Gene : Slco2b1 solute carrier organic anion transporter family, member 2b1

Primary Identifier  MGI:1351872 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  101488
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables organic anion transmembrane transporter activity. Predicted to be involved in organic anion transport and transmembrane transport. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in basal plasma membrane. Predicted to be active in apical plasma membrane and basolateral plasma membrane. Is expressed in blood vessel; brain meninges; and embryo. Orthologous to human SLCO2B1 (solute carrier organic anion transporter family member 2B1).
PHENOTYPE: Mice homozygous for a knock-out allele develop to adulthood normally but show increased blood urea nitrogen level and decreased absorption of fluvastatin, a known SLCO2B1 substrate drug. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI852653,
  • solute carrier organic anion transporter family, member 2b1,
  • OATP-B,
  • AI060904,
  • Slco2b1,
  • Slc21a9,
  • solute carrier family 21 (organic anion transporter), member 9,
  • expressed sequence AI060904,
  • MGI:2141865,
  • AI852653,
  • MGI:2142064

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For