Primary Identifier | MGI:1351872 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 101488 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables organic anion transmembrane transporter activity. Predicted to be involved in organic anion transport and transmembrane transport. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in basal plasma membrane. Predicted to be active in apical plasma membrane and basolateral plasma membrane. Is expressed in blood vessel; brain meninges; and embryo. Orthologous to human SLCO2B1 (solute carrier organic anion transporter family member 2B1). PHENOTYPE: Mice homozygous for a knock-out allele develop to adulthood normally but show increased blood urea nitrogen level and decreased absorption of fluvastatin, a known SLCO2B1 substrate drug. [provided by MGI curators] |