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Protein Coding Gene : Slco2a1 solute carrier organic anion transporter family, member 2a1

Primary Identifier  MGI:1346021 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  24059
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables prostaglandin transmembrane transporter activity. Acts upstream of or within prostaglandin transport. Predicted to be located in basal plasma membrane. Predicted to be active in basolateral plasma membrane. Is expressed in several structures, including ganglia; nose; renal cortex; respiratory system; and skin. Human ortholog(s) of this gene implicated in primary hypertrophic osteoarthropathy. Orthologous to human SLCO2A1 (solute carrier organic anion transporter family member 2A1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit preinatel or early psotnatal lethality due to a patent ductus arteriosus and abnormal protaglandin metabolism. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2310021C19 gene,
  • Slc21a2,
  • solute carrier organic anion transporter family, member 2a1,
  • MGI:1915306,
  • solute carrier family 21 (prostaglandin transporter), member 2,
  • Pgt,
  • Slco2a1,
  • 2310021C19Rik,
  • mPgt

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For