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Protein Coding Gene : Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1

Primary Identifier  MGI:98898 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  394436
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable several functions, including glucuronosyltransferase activity; protein dimerization activity; and retinoic acid binding activity. Predicted to be involved in several processes, including biphenyl catabolic process; cellular glucuronidation; and negative regulation of cellular glucuronidation. Predicted to act upstream of or within lipid metabolic process. Located in plasma membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in alimentary system; liver; nervous system; and urinary system. Human ortholog(s) of this gene implicated in several diseases, including bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; female reproductive organ cancer (multiple); and hepatitis B. Orthologous to human UGT1A1 (UDP glucuronosyltransferase family 1 member A1).
  • synonyms:
  • Ugt1a1,
  • glucuronosyltransferase, phenol-UDP,
  • UGT1A01,
  • MGD-MRK-15340,
  • onosyltransferase, phenol-UDP,
  • UgtBr1,
  • MGD-MRK-10210,
  • UDP glucuronosyltransferase 1 family, polypeptide A1,
  • Udpgt-1a,
  • Gnt1,
  • MGD-MRK-15345,
  • UDP-glucuronosyltransferase 1a

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

1 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For