Primary Identifier | MGI:3653698 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Kcnd2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to replace all of exon 1 with a neomycin resistance gene. Northern blot analysis failed to detect transcript in mutant brain, heart or liver samples. Western blot failed to detect protein in mutant hearts. |