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Comment :

Type  MGI:General Description  no (0/5) detectable outgrowths at 5 weeks after orthotopic transplantation of mammary anlagen collected from E14 embryos vs 50% (3/6) of the wild-type anlagen 0% (0/9) of the mutant anlagen vs 59% (10/17) of the wild-type form mammary ductal outgrowths at 8 weeks post-transplant when exposed to pregnancy-associated hormones, all the mutant mammary anlagen fail (0/9) to develop, whereas 71% (5/7) of the wild-type anlagen form outgrowths with extensive alveoli no puberty-associated mammary morphogenesis (TEBs) at 2 weeks and 4-5 weeks after renal capsule grafting of postnatal day 1 glands