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Publication : A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9.

First Author  Kashiwaba M Year  2003
Journal  FEBS Lett Volume  538
Issue  1-3 Pages  197-202
PubMed ID  12633878 Mgi Jnum  J:82289
Mgi Id  MGI:2651995 Doi  10.1016/s0014-5793(03)00153-4
Citation  Kashiwaba M, et al. (2003) A novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9. FEBS Lett 538(1-3):197-202
abstractText  In this study we have cloned a novel member of mouse protein phosphatase 2C family, PP2Czeta, which is composed of 507 amino acids and has a unique N-terminal region. The overall similarity of the amino acid sequence between PP2Czeta and PP2Calpha was 22%. On Northern blot analysis PP2Czeta was found to be expressed specifically in the testicular germ cells. PP2Czeta expressed in COS7 cells was able to associate with ubiquitin conjugating enzyme 9 (UBC9) and the association was enhanced by co-expression of small ubiquitin-related modifier-1 (SUMO-1), suggesting that PP2Czeta exhibits its specific role through its SUMO-induced recruitment to UBC9.
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