| Primary Identifier | IPR008963 | Type | Homologous_superfamily |
| Short Name | Purple_acid_Pase-like_N |
| description | Purple acid phosphatases (PAPs) are ubiquitous binuclear metal-containing acid hydrolases characterised by their acidic pH optima and their intense purple colour due to a TyrO-to-FeIII charge-transfer transition. The amino acid residues coordinating the metal ions are conserved in all PAPs. Active PAPs contain an FeIII ion coordinated to Tyr O, a His N, and an Asp O2, in addition to a divalent metal ion (Fe, Zn, or Mn) coordinated by a His N, a His N, and an Asn O. A hydroxide ion and an Asp O2bridge the two metal ions []. These enzymes share a high degree of homology within their N-termini [].This entry also includes phospholipase D, the structure of which has been solved from Bacillus subtilis and shows a purple acid phosphatase-like fold []. |
