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Allele : Tnfrsf4<tm1Nik> tumor necrosis factor receptor superfamily, member 4; targeted mutation 1, Nigel Killeen

Primary Identifier  MGI:1859871 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnfrsf4
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette was used to replace four exons, which code for the first 143 amino acids of the protein. Activated T cells from homozygous mutant animals lacked expression of Tnfrsf4 as detected by flow cytometry with the OX86 mAb as well as a soluable ligand fusion protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • OX40-,
  • OX40 KO,
  • CD134-,
  • CD134-,
  • OX40-,
  • OX40 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

49 Publication categories

Trail: Allele