| Primary Identifier | MGI:103298 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 11810 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables mRNA 3'-UTR AU-rich region binding activity. Involved in DNA demethylation; cytidine to uridine editing; and negative regulation of DNA methylation-dependent heterochromatin formation. Acts upstream of or within several processes, including lipoprotein transport; mRNA stabilization; and negative regulation of triglyceride metabolic process. Predicted to be part of apolipoprotein B mRNA editing enzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in early conceptus; genitourinary system; and liver. Orthologous to human APOBEC1 (apolipoprotein B mRNA editing enzyme catalytic subunit 1). PHENOTYPE: Mice homozygous for a null allele exhibit abnormal lipid homeostasis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
