| Primary Identifier | MGI:3579139 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Lpar3 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The 5' UTR, start codon and first 26 amino acids in exon 2 was replaced with a neomycin resistance gene in reverse orientation. Two types of truncated transcript were detected in mutant testis or kidney of by RT-PCR, one having the undeleted region of exon 2 and full-length exon 3, and the other having exons 1 and 3, but not 2. Western blot failed to detect corresponding proteins for these transcripts, indicating that neither can be properly translated. |
